Controlled Substance Ordering System (CSOS)

DEA’s Controlled Substance Ordering System (CSOS) facilitates the electronic ordering of controlled substances in Schedules I through V. It allows for a secure electronic transmission of controlled substance orders without supporting documents previously required.

The DEA will be launching the new CSOS on December 9, 2024, which will change how DEA registrants request CSOS enrollment and additional users. Stay tuned for virtual training sessions by checking Diversion Control’s upcoming events.

CSOS Enhancements—Letter to Practitioners (October 16, 2024)

CSOS Enhancements—Letter to all other registrants (October 15, 2024).

The system is designed to provide services to DEA-registered pharmaceutical drug manufacturers and distributors, pharmacies, hospitals, and others to transmit customers’ orders electronically.

To access CSOS, go to: https://www.deaecom.gov/